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This is a regulatory mechanism that goes on all the time which skews carbohydrate metabolism toward cytoplasmic reduction of pyruvate to lactate under aerobic conditions.[ref] Pyruvate is converted in the Krebs cycle (mitochondria) to acetyl-CoA, and this conversion is tightly regulated to prevent too much acetyl-CoA

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Sensors and Actuators B: Chemical 332:129513 Deng Z, Li X, Liu H et al (2020) A nanoprobe for ratiometric imaging of glutathione in living cells based on the use of a nanocomposite prepared from dual-emission carbon dots and manganese dioxide nanosheets

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