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Upadhyay, Applied Surface Science 385, (2016) 225233

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The first and rate-limiting step of GSH synthesis is catalyzed by glutamate-cysteine ligase, which is regulated by cysteine availability at the level of transcription and translation 6

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APAP biotransformation to NAPQI was achieved using rat liver microsomes or human cytochrome P450 Supersomes in the presence of GSTA1, M1, M2, or P1

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