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NICE guidance recommends early referral (within 3 working days) for suspected persistent synovitis to enable prompt initiation of disease-modifying therapy where appropriate

10.2119/molmed.2013.00009 73

Various PYY analogues have been created including intravenous, oral or nasal formulations

KPV (LysineProlineValine): A naturally occurring tripeptide derived from -Melanocyte-stimulating hormone (-MSH), widely investigated in scientific studies examining anti-inflammatory pathways, immune modulation, and cell signalling mechanisms (Wikipedia: Alpha-Melanocyte-Stimulating Hormone)