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GPX4 is also known as phospholipid hydroperoxide and exists as cytosolic, mitochondrial, and nuclear isoforms

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There is already an exceptional knowledge about the mechanisms by which copper and mutations within the ATP7B gene develop their pathogenic properties during onset and progression of Wilson disease (96,97)

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C (101 MHz, CDCl 3 ) 171.09 (C), 134.80 (t, J = 23.8 Hz, CD), 133.12 (td, J = 24.8, 9.9 Hz, CD), 130.22 (td, J = 24.7, 12.5 Hz, CD), 117.87 (d, J = 85.8 C), 38.67 (CH 2 ), 38.37 (CH 2 ), 27.54 (CH 2 ), 26.86 (d, J = 16.7 Hz, CH 2 ), 22.31 (d, J = 51.3 Hz, CH 2 ), 21.72 (d, J = 4.3 Hz, CH 2 )