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The three main curcuminoids found in turmeric are: Curcumin (diferuloylmethane) : The most abundant and biologically active curcuminoid Demethoxycurcumin (DMC) : Shows antioxidant and anti-cancer activity Bisdemethoxycurcumin (BDMC) : Adds to the anti-inflammatory effects and may have synergistic activity These compounds work best together, and the most effective supplements include all three in a concentrated and bioavailable form

Size-dependent Proinflammatory effects of ultrafine polystyrene particles: a role for surface area and oxidative stress in the enhanced activity of ultrafnes