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Mol Endocrinol 14 : 650661 Lee PD (1996) A randomized, placebo-controlled trial combined insulin-like growth factor I and low dose growth hormone therapy for wasting associated with human immunodeficiency virus infection

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flavone glycoside) The first focused review in 2025 positions prunin as emerging anticancer candidate that modulates cell cycle and apoptosis pathways, with early evidence for combination use and nanoformulations to overcome solubility/bioavailability limits (Rana and Mumtaz, 2025)