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coli cells are cultured aerobically in rich media such as the Luria-Bertani (LB) broth, the availability of nutrients supports rapid growth via glycolysis, the pentose phosphate pathway (PPP) and the tricarboxylic acid (TCA) cycle 48

Interestingly, SARS-CoV-2 employs a rapid pH-independent pathway to enter and infect cells in the presence of TMPRSS2

Indeed, high exposure may sometimes attenuate efficacy via the hook effect

In the first phase, the increase in glucose transport rate, independent from insulin presence, is mediated by the translocation, induced by the contraction, of glucose transporters, called GLUT4, on the cytoplasmatic membrane of the muscle cell

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