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Rats received AOD 9604 daily for 6 months and cynomolgus monkeys for 9 months

Vitamin B12 deficiency treatment is often recommended if you experience fatigue, weakness, or nerve-related symptoms

Additionally, NNMT inhibition appears to increase expression of GLUT4 transporters, which move glucose from the bloodstream into cells

However, its important to note that 24 weeks, while substantial for clinical trials, represents a relatively limited timeframe for assessing lifetime exposure safety