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Autoinhibition of Jak2 tyrosine kinase is dependent on specific regions in its pseudokinase domain

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Interstitial Cystitis, PL 14736, and Reported Outcomes A 2024 pilot study reported 12 women with interstitial cystitis who received a total of 10 mg intravesical BPC-157 during a single procedure, with 10 of 12 reporting complete symptom resolution and two reporting 80% improvement