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found that the downregulation of CD44 led to a decrease in -catenin expression, thereby inducing leukemia cell cycle to arrest in the G0/G1 phase, where gene transcription is blocked, and cell proliferation is inhibited (101)

Targeting mitochondria in therapy: toxicity, mechanistic ambiguities, and translational barriers Although mitochondrial-targeted therapies have shown great potential in various cancers, they still face significant challenges in clinical advancement

Chem Commun (Cambridge England) (2021) 57(49):60469

Structural properties of EGCG-induced, nontoxic Alzheimers disease A oligomers

ROS, which include superoxide, nitric oxide, hydroxyl radical, hydrogen peroxide, and peroxynitrite, can be generated from various sources including the electron transport chain or activated immune cells