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Nuclear factor (erythroid-derived 2)-like 2 (NRF2) is the major modulator that negatively regulates ferroptosis by increasing iron storage and inhibits ROS production [23]

Immune-mediated processes implicated in chemotherapy-induced peripheral neuropathy

Furthermore, CAT has many industrial applications, such as (1) in the food sector to remove hydrogen peroxide milk before cheese production, (2) in food wrappers to prevent food deterioration, (3) in the textile industry to ensure that materials are peroxide free by removing hydrogen peroxide from fabrics, (4) in contact lenses for cleaning purposes using a hydrogen peroxide solution, and (5) In the beauty sector, masks are treated with CAT and hydrogen peroxide on the face to promote cellular oxygenation in the upper layers of the epidermis [97, 98]

In MLC, astrocytes show impaired K + buffering, glutamate uptake and ionic homeostasis, which translate into white matter damage in a yet uncharacterized way 339,342,343

doi: 10.1038/s41392-022-00917-z 137 CuiYZhangYZhaoXShaoLLiuGSunCet al