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In another study, rats with diabetic kidney disease (DKD) were treated with a CD38 inhibitor, resulting in increased renal NAD + levels, which in turn decreased mitochondrial oxidative stress 144

Metab Brain Dis 36(7):19571968

Epithelial STAT6 O-GlcNAcylation drives a concerted anti-helminth alarmin response dependent on tuft cell hyperplasia and gasdermin C

PubMed Boettcher S, Miller PG, Sharma R, McConkey M, Leventhal M, Krivtsov AV, Giacomelli AO, Wong W, Kim J, Chao S, Kurppa KJ, Yang X, Milenkowic K, Piccioni F, Root DE, Rcker FG, Flamand Y, Neuberg D, Lindsley RC, Jnne PA, Hahn WC, Jacks T, Dhner H, Armstrong SA, Ebert BL

The cure is usually rest, barrier repair, and a more careful reintroduction at a lower frequency