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"The Effect of Aging, Nutrition, and Exercise during HIV Infection." HIV AIDS (Aukl) 2 (2010): 191-201

2020;6:eabc2487

The inhibition of serine and glycine bidirectional conversion by sertraline prior irradiation reduces the pool of nucleotides, as we previously observed, and concurrent and post-treatment with sertraline might hinder the synthesis of the antioxidant GSH and NADPH production, which exposes cancer cells to the accumulation of endogenous ROS and radiation-induced ROS causing severe oxidative stress [70]