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Building on these core therapeutic mechanisms, Clostridium -based interventions exhibit clear stratified clinical positioning in ADs, with their therapeutic significance defined by evidence maturity and disease-specific pathological characteristics, serving as a complement rather than a substitute for conventional therapies

Effects vary depending on individual hydration, nutrition and lifestyle

TSPO was correlated with higher Tau and network dysfunction, independent of A [283, 284]

In the external modification of bacteria, the chemical coupling strategy based on covalent bonds can stably and irreversibly link functional molecules to the bacterial surface through specific chemical reactions [116]

it can happen because of many reasons including direct exposure to UV radiation on exposed areas of skin, immunogenic skin problems, DNA damage due to various reasons, skin color, sun tanning bed, and many more