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First isolated from human plasma in the early 1970s, it has been studied extensively for its role in tissue repair, collagen synthesis, and antioxidant signaling

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Nevertheless, in cases of severe deficiency with neurological sequelae, we suggest that IM B12 is used in the first instance to replenish body stores with the treatment regimen, including dosage and formulation, optimised to keep the patient free of symptoms and tailored to the metabolic response of not only plasma B12 levels, but also confirmatory testing of homocysteine, methionine, and methylmalonic acid levels

Discovery of the curcumin metabolic pathway involving a unique enzyme in an intestinal microorganism

"Pernicious" means "harmful" or "destructive." This type of B12 deficiency anemia can affect many body systems and cause problems in your gut, heart, and muscles