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Development of pegylated liposomal vincristine using novel sulfobutyl ether cyclodextrin gradient: is improved drug retention sufficient to surpass DSPE-PEG-induced drug leakage

doi: 10.1016/j.biopha.2013.04.005

10.1046/j.1471-4159.2002.01041.x 181

L., Hazen, S

The two models we have used in this study are different in that one involves global germ line deletion of the D 2 R while the other involves a 7-day renal subcapsular infusion of Drd2 siRNA in the remaining kidney of uninephrectomized mice that decreases renal D 2 R expression by 6070%