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83 Tivanitib, an oral selective c-Met inhibitor, showed encouraging responses in preclinical studies and a phase II clinical trial, but a subsequent phase III trial in advanced HCC with high c-Met expression did not demonstrate similar effects

Ethanol-related metabolites (acetaldehyde and acetate) and oxidative stress generated during alcohol metabolism are primary contributors to ALD [19]

The heavy and light chains were cloned in a pETDuet vector (Addgene plasmid #136144) with a N terminus pelB signal sequence for both the heavy and light chain

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V., Papagiannakopoulos, T., Davidson, S