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Description

This review discusses the therapeutic potential of natural flavonoids from herbs and nutraceuticals as ferroptosis inhibitors in CNS diseases, focusing on their molecular mechanisms, summarizing findings from preclinical animal models, and providing insights for clinical translation

3.1.3 LPS The gut microbiota-derived metabolite LPS translocates into systemic circulation in HF patients via intestinal barrier dysfunction, triggering systemic inflammation and exacerbating cardiac injury