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In fact, sensitivity was mostly limited to worst-case scenarios of highly thinned down mixtures (1:20 and 1:100) involving pigments like Raw Umber, which has a high clay content, or the more dye-like Anthraquinone Blue

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The irreversible electrical coagulation of the distal segment of the left middle cerebral artery was performed under anesthesia with chloral hydrate (300 mg/kg)