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Description

This study describes the in vitro generation of otic neuroprogenitors that can differentiate into hair cells and sensory neurons

A eukaryotic-type signalling system of Pseudomonas aeruginosa contributes to oxidative stress resistance, intracellular survival and virulence

Deeply hydrates for healthy skin texture

doi: 10.1126/science.1234089

Unlike existing reviews that primarily discuss PROTAC biology, degrader chemistry, or delivery systems in a more general manner, this review focuses specifically on the chemistry-guided design logic of smart delivery systems for PROTACs and on how the unique structural and physicochemical features of PROTACs impose distinct delivery requirements