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Supplementary Materials Rights and permissions About this article Cite this article Li, X., Yan, W., Li, J

Cioni et al., 2021)

The t -test indicated a statistical difference between the two groups, confirming that GSH reserves are markedly depleted in hypoxic hepatic tissues [t 22 = 3.5, p = 0.003]

This entire process prevents the cell from producing misfolded or altered proteins.[ref] Studies show that high homocysteine levels cause ER stress and activate the unfolded protein response pathway, which can lead to cell death