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The conceptual basis of 5-FU has been used to develop a thymidine analog, trifluorothymidine (TFT), as discussed below

Chan School of Public Health, Boston, Massachusetts, USA

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PRDX enzymes primarily regulate ROS generated during TCR signalling, rather than ROS produced during overt stress responses

In addition, these investigations predominantly focused on the GBM subtype of brain cancer, thereby restricting the extrapolation of their findings to other histological subtypes