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A key randomized, double-blind, placebo-controlled crossover trial revealed that NR supplementation (1000 mg daily) for 6 weeks increased blood cellular NAD+ concentrations by approximately 60% compared to placebo [4]

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10.1038/nrendo.2013.255 3

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J Pharm Innov 21 , 280 (2026)

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(2016) 95:e2536

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Because structural features of DAI are difficult to detect by traditional computed tomography (CT) or magnetic resonance imaging (MRI) scans (Maruta et al, 2010), mTBI is not easily diagnosed in the acute stage, and in fact may go unnoticed until the emergence of postconcussion symptoms (Maruta et al, 2010)

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