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E-resistance indicates biophysical characteristics of spatial position changes of e-transfer centers as Fe and Cu in the complexes independent of driving force.To elucidate the location of the conformational changes, location site of specific inhibitors and the inhibitory mechanisms of reduction of activating energy at each catalytic site were studied

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HIV Protease Inhibitors (Ritonavir and Atazanavir) HIV medications such as ritonavir and atazanavir also inhibit CYP3A4

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