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Different types of exposures are suggested to impact differently on biological pathways related to psychosis, i.e ., stimulation exposures characterized by heightened chronic physical arousal and vigilance could evoke feelings of threat and symptoms of paranoia affecting the structure, function, and connectivity of threat circuit regions, including the amygdala, hippocampus, and ventromedial prefrontal cortex

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In skeletal muscle, AKT phosphorylation activates mTORC1, increasing ribosomal protein S6 kinase activity and protein translational efficiency the primary molecular mechanism underlying the hypertrophic stimulus

Abern MR, Levine LA