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Additionally, the inhibition of LAMP2 A reduced cytokine release and heightened sensitivity to temozolomide, alongside in vivo studies confirming reduced tumorigenicity and increased lifespan in murine models [282]

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Two independent Py-GC-MS runs were made at separate APCI source skimmer cone voltages (fragmentation parameters): 95 V to limit fragmentation and 200 V to achieve in-source CID

The field is still trying to parse out which epigenetic changes are associated with MS and what causes them

The raw dataset was uploaded to www.ebi.ac.uk/metabolights/MTBLS5401