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How distinct intracellular GSH pools are differentially controlled, how flux between compartments is coordinated, and how these dynamics influence commitment to apoptosis, ferroptosis, and cuproptosis remain incompletely understood

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Acoustic stimulation decreases hair cell synapse number Cochlear hair cells exposed to moderate noise trauma exhibit a reduction in synaptic ribbons and an increase in orphaned ribbons that are unpaired with a post synaptic density (Kujawa and Liberman, 2009

2023) as well as to the detoxification of reactive oxygen species and toxins (Almeida et al