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Description

It is of note that z-VAD-FMK, a pan-caspase inhibitor [27], does not exhibit any protection against BSO-induced cell death

The mechanism of this protection at least partially lies in the role of Parkin/PINK1-mediated mitophagy that is progressively unravelled and refined

Free Radical Biology & Medicine 45 (9): 120516

The systems were thermally relaxed before the production run using the Nose-Hoover Chain thermostat method for 5 ns and 5 ns of pressure relaxation with the Martyna-Tobias-Klein barostat method