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PMID: 34237343

Pharmacologic inhibition of AKT by treatment with the AKT inhibitor MK2206 significantly decreased GSH levels in untreated TrC1 AKT-E17K cells and almost abrogated GSH levels 12 h after irradiation, and this was associated with a significantly increase in radiosensitivity

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[7] In fact, one report highlighted depleted levels of glutathione associated with increased susceptibility to infections like chronic obstructive pulmonary disease, cystic fibrosis, influenza, and AIDS

3068-A DIASTOLIC DYSFUNCTION IN CIRRHOTIC CARDIOMYOPATHY: A PROSPECTIVE OBSERVATIONAL COHORT STUDY ON SHORT-TERM OUTCOMES IN CIRRHOTIC PATIENTS UNDERGOING TIPS Yaozu Liu 1,2,3 , Fangmin Meng 1,4 , Wen Zhang 1,2,3 , Jingqin Ma 1,2,3 , Zhiping Yan 1,2,3 , Cuizhen Pan 1,4 and Jianjun Luo 1,2,3,5 , (1)Shanghai Institute of Medical Imaging, (2)Department of Interventional Radiology, Zhongshan Hospital, Fudan University, (3)National Clinical Research Centre for Interventional Medicine, Zhongshan Hospital, Fudan University, (4)Department of Echocardiography, Zhongshan Hospital, Fudan University, (5)Centre for Tumor Diagnosis and Therapy, Jinshan Hospital, Fudan University Background: The placement of Transjugular intrahepatic portosystemic shunt (TIPS) results in a sudden increase in central circulating blood volume, which requires proper regulation of the cardiovascular system