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Recent advances in neuroimaging technology allowing for in vivo quantification of GSH levels in the brain have shown decreased GSH in patients with MS compared to healthy controls, with the degree of depletion correlating with disease severity and showing parallel longitudinal decline over time (Choi et al., 2018

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Measurement of sulfur-containing metabolites by ultra-performance liquid chromatographymass spectroscopy In total, 1 10 6 cells (Pfa1 xCT OE) or 2 10 6 cells (HeLa) were seeded in 10-cm dishes in DMEM with 10% FCS