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KuznietsovaHGlonADziubenkoNZaderkoASergeiALysenkoVet al In Vitro and In Vivo Toxicity of Carbon Dots with Different Chemical Compositions

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As can be seen in Figure 2, NAD + relies on the CD38/CD203a tandem and CD73 ectonucleotidase to activate a discontinuous multicellular pathway for ADO production, as detected in plasma aspirates from myeloma BM ( The cyclic nucleotide cAMP signaling pathway is a third alternative route to the production of extracellular ADO (Figure 1)

doi:10.1097/SAP.0b013e318206595b Mendieta CG

For MMUT to function properly, a third protein, MMAA, is required to protect MMUT against oxidative stress and to reactivate the enzyme [107]