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In terms of epigenetics [161], methylation mediated by SAM increases ferroptosis in rheumatoid arthritis by enhancing the GPX4 promoter in response to glycine

doi: 10.1002/(SICI)1099-0844(199712)15:4 3.0.CO;2-1 194 LiuSZhangSHongLDiaoLCaiSYinTet al

6c, Supplementary Fig

Furthermore, EpiCor exerts profound effects on the gut-immune axis

Xiaoyaosan improves antibiotic-induced depressive-like and anxiety-like behavior in mice through modulating the gut microbiota and regulating the NLRP3 inflammasome in the colon