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Data management & statistical analysis Sample size calculations were based on previous oral wound healing study outcomes for CWE prevalence on day 7 [25], and indicated that a study with 22 participants (11 per group) would have 80% power, at 5% significance level (two-sided), to detect a significant difference between the two groups, assuming a 55% difference in CWE incidence

Of which, Parkinsons disease (PD) is a progressive neurological ailment characterized by disturbed motor and non-motor functions

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To ensure that the total number of units is determined only using PDE records that accurately reflect the actual quantity dispensed of the Part D rebatable drug, we are finalizing at 428.203(b)(3) that, for operational reasons at this time, CMS will exclude PDE records for Part D rebatable drugs that were billed as compounds when determining the total number of units of each Part D rebatable drug dispensed under Part D and covered by Part D sponsors