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Many commercial plans require Modifier 59 (distinct procedural service) when 96372 is billed alongside other procedure codes on the same date, particularly if the injection is being performed at the same anatomical site as a concurrent service

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For example, a randomized controlled trial (RCT) found that applying curcumin gel into periodontal pockets after SRP significantly reduced probing depth and gingival inflammation, and lowered IL-1 in crevicular fluid compared to SRP alone (Mohammad, 2020)

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In this regard, as 15LO1 increased, GPX4 expression concomitantly increased to balance the high 15LO1 activity (Figure 2C)