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Accordingly, mitochondrial dysfunction can lead to early signs of neurodegeneration or synaptic deficits, as well as distinct cognitive deficits without A deposits being present, a new situation recently called Suspected non-amyloid pathology (SNAP)

L-Carnitine and its short-chain esters do not bind to plasma proteins and, although blood cells contain L-carnitine, the rate of distribution between erythrocytes and plasma is extremely slow in whole blood

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CD44-HA interactions facilitate targeted delivery of the cargo to retinal cells via the active endocytosis of HA-coated agents, a process that is efficient for the uptake of larger NPs and makes HA a biologically active polymer [154, 163, 164]

Mitochondrial Biogenesis Slu-pp-332 and 5-Amino-1MQ are investigated for their roles in stimulating new mitochondrial creation and improving cellular respiration, supporting enhanced energy efficiency