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Most protocols use 13mcg/kg as the working range: 1mcg/kg produces measurable GH elevation with minimal desensitisation risk, 2mcg/kg generates peak amplitude responses in most subjects, and 3mcg/kg approaches the ceiling dose beyond which additional peptide does not proportionally increase GH output

Homocysteine, as noted in this article, if its too low could be too much methylation support (such as B12 and methylfolate) may cause levels to decrease too far

The ALMS1 gene that encodes for a ubiquitously expressed protein has been proved to be associated with cell cycling and energy metabolism

Lin YT, Lin J, Liu YE, Chen YC, Liu ST, Hsu KW et al