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No se han identificado transportadores para el glutamato en la membrana del eritrocito (5) y ha sido propuesto que el glutama-to eritrocitario deriva de la glutamina o de la transa-minacin del a-cetoglutarato (29), en tanto que en el hepatocito el glutamato ingresa transportado por el transportador aninico X AG (17)

The pathway enrichment and pathway network topology analysis revealed that 14 metabolic pathways related to glaucoma, including glycine and serine metabolism, alanine metabolism, galactose metabolism, methionine metabolism, glutathione metabolism, purine metabolism, glutamate metabolism, urea cycle, spermidine and spermine biosynthesis, biotin metabolism, ammonia recycling, fructose and mannose deregulation, homocysteine deregulation and nucleotide sugar metabolism were significant (Figures 4A,B)

Zhou JN, Liu RY, Kamphorst W, Hofman MA, Swaab DF

Silibinin-induced mitochondria fission leads to mitophagy, which attenuates silibinin-induced apoptosis in MCF-7 and MDA-MB-231 cells