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LAT1 is overexpressed in several cancers, including glioblastoma [76], brain metastases [77], and various solid tumors, as well as in neurological disorders, such as autism spectrum disorders [78]

10.1002/chem.201202398 70 MarquesH

After the 10 days of adaptation, the mice were randomized into fourteen groups of 8 mice (body weight was 23.2 1.2 g)

CAR-T cells have a particular effect in treating solid tumors such as renal cell carcinoma, HER2 positive sarcoma, ovarian cancer (94), and colorectal cancer (95)