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Metabolic crosstalk between cancer and the tumor microenvironment (TME) Hypoxia and metabolic adaptation Hypoxia, a characteristic feature of solid tumors, profoundly shapes the metabolic landscape of NSCLC

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Intermittent hypoxic mice were treated with 10 cycles of 5-min 13% O 2 (hypoxia) and 5-min 21% O 2 (normoxia) per day for 14 days, followed by an additional continuous hypoxic treatment

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