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Together, these results indicate that decreased GSH/GSSG redox/antioxidant capacity and increased oxidative stress in the autism brain may have functional consequence in terms of a chronic inflammatory response, increased mitochondrial superoxide production, and oxidative protein and DNA damage

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146 Another phase I b clinical trial also showed good tolerability and clinical activity of TelaE or telaglenastat combined with cabozantinib (TelaC) in treating RCC