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Growth and neurotrophic factors CSF Brain Derived Neurotrophic Factor (BDNF) levels have been found to be similar in PD patients with major depression to those in patients with major depression without PD in one study (Plhagen et al., 2010), while another described this value as increased in PD patients compared with controls (Salehi and Mashayekhi, 2009)

Yang M-Y, Song Z-Y, Gan H-L, Zheng MH, Liu Q, Meng XT, Pan T, Li ZY, Peng RX, Liu K, Fan HY (2022) Non-clinical safety evaluation of salvianolic acid A: acute, 4-week intravenous toxicities and genotoxicity evaluations

Portero-Tresserra M, Galofr-Lpez N, Pallares E, Gimenez-Montes C, Barcia C, Granero R, Rojic-Becker D, Vale-Martnez A, Mart-Nicolovius M, Guillazo-Blanch G (2023) Effects of caloric restriction on spatial object recognition memory, hippocampal neuron loss and neuroinflammation in aged rats

PubChem CID 92432 records molecular formula C 50 H 69 N 15 O 9 , MW 1024.2 g/mol, and monoisotopic mass 1023.54026884 Da

As is typical for many toxicology interventions, there may never be a randomized controlled trial