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highlighted that KRAS mutation increased IGF1R expression at both the mRNA and protein levels through Y-box-binding protein-1 (YB-1) upregulation which was then validated as a miR-137 target gene

M.BastianelliS.GiustariniD.PierucciS.BustiC.et al

Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis

By targeting melatonin synthesis and circadian gene expression, Epitalon could act as a molecular metronome, realigning internal timekeeping mechanisms that tend to falter with age

Transferrin receptor as a glycoprotein, has two subunits of 90 kDa linked by a disulfide bridge, participating in the transcytosis of cellular iron by each subunit is capable of binding to one molecule of transferrin