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The copper ion is chelated primarily through the imidazole nitrogen of histidine and the alpha-amino nitrogen of glycine, creating a stable, biologically active complex

Dev Neurosci 22:384392 Hirrlinger J, Resch A, Gutterer JM, Dringen R (2002) Oligodendroglial cells in culture effectively dispose of exogenous hydrogen peroxide: comparison with cultured neurones, astroglial and microglial cells

Shaw LT, Mackin A, Shah R, Jain S, Jain P, Nayak R et al (2020) Risuteganiba novel integrin inhibitor for the treatment of non-exudative (dry) age-related macular degeneration and diabetic macular edema

Our findings demonstrate that the reaction conditions can be flexibly optimized not only for the synthesis of proteins with disulfide bonds but also for proteins requiring a reduced state