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The liver wet weight was recorded to estimate the liver index employing the formula: One portion of the liver was homogenized for the quantification of oxidative stress markers (reduced glutathione [GSH] and malondialdehyde [MDA])

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Bicyclol reduces the activation of NF-B and the levels of inflammatory factors in hepatocytes infected with hepatitis C virus (HCV) by inhibiting the activation of the ROS-MAPK-NF-B pathway, and prevents ferroptosis in acute liver injury