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OLE treatment also resulted in the reduced expression of the pro-adhesive molecules E-selectin and VCAM-1 in HCAECs and human umbilical vein endothelial cells (HUVECs) following pro-inflammatory stimulation with LPS, TNF-, and PMA (160)

It is also heavily concentrated in the liver, where it plays a central role in the detoxification process, helping the body filter and eliminate waste products

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Impact of systemic to topical steroids switch on the outcome of drug reaction with eosinophilia and systemic symptoms (DRESS): a monocenter retrospective study of 20 cases