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The concordance of our patient's serologic profile and clinical course with these reports supports the consistency of methimazole-induced lupus as a recognizable clinical entity in pediatrics and highlights the importance of vigilance, particularly in the first few weeks of treatment

Discussion CRISPRCas9 is an RNA-guided gene-editing tool that offers several advantageous characteristics in comparison with the conventional methods (e.g., zinc finger nucleases and transcription activator-like effector nucleases)

Crawford A and Harris H

Additionally, AMDs pathogenesis involves the loss of RPE-derived VEGF signaling and defenestration of usually high permeable choriocapillaries in atrophied RPE areas, which disrupts retinal permeability [440, 441]