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Reactions that warrant attention include persistent swelling or redness lasting more than 24 hours, significant pain beyond the initial injection moment, the development of hard nodules that do not resolve within a day or two, fever or systemic symptoms following injection, or any sign of infection at the injection site including warmth, pus, or spreading redness

Primary Handling Editor: Isabella Samuelson, in collaboration with the Nature Metabolism team

Chopra S, Bosse T, Horeweg N, Deodhar K, Menon S, Rafael T, et al

This study showed effects at very low concentrations (picomolar to nanomolar), which is encouraging for topical application

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