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It has to be noted however that gain of function may also develop in parallel with loss of function, with reactive astrocytes for example losing their ability to clear glutamate in the context of motor neurone diseases

Such transcriptional reorganization is consistent with an adaptive remodeling process rather than an acute stress response and provides a plausible molecular basis for the altered migratory behavior observed following cold acclimation

Vitamin B12 can be found in animal based foods, fortified foods such as cereals and through oral vitamin supplements

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