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At the same time, IGF1R activates the PI3K/Akt signaling pathway, promotes Bcl-2/Bax expression and inhibits cell apoptosis (Katayama et al., 2007) (Figure 4B)

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Key Research Facts: Semax vs Selank at a Glance Both peptides are 7 amino acids (heptapeptides) in length Semax increases BDNF by up to 80% in some animal models (per Russian research) Selank mimics the bodys natural tuftsin peptide, supporting immune and neural regulation Both are approved medications in Russia and Ukraine for clinical use Neither is currently FDA-approved

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