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Alonso Cnovas A, Luquin Piudo R, Garca Ruiz-Espiga P, et al

Further, research will help better define their physiological roles and significance

Emerging PTMs such as SUMOylation, O-GlcNAcylation, lactylation and succinylation have recently been implicated in redox regulation and metabolic stress adaptation in other disease contexts

alpha-synuclein accumulation in SH-SY5Y cell impairs autophagy in microglia by exosomes overloading miR-19a-3p

It has been shown that, during chemotherapy, tumor cells could overcome drug-induced OS by enhancing their antioxidant systems as well as an increasing P-gp pump efflux to acquire a new redox balance due the increased ROS accumulation and antioxidant systems in a process of redox rearranging (see Figure 1)